CMS healthcare programs are shifting from an optional data reporting submissions to mandatory electronic submissions. To meet these requirements, healthcare organizations need to align their organization’s data with evolving standards, which can require a whole-system transformation.This is the first of three articles that stress the urgent need for healthcare systems to take an all-in approach to data and analytics, starting with the need for and benefits of high-value data.High-value data has been standardized and can be used to identity standardized attributes across previously siloed systems. It enables: faster downstream analytics, aggregated benchmarking, novel data combinations that produce exponential value.Organizations that make high-value data the foundation of an integrated data strategy, can supply providers, clinicians, and administrative leaders with the trusted, timely data they need to maximize reimbursement and drive informed decisions for better outcomes.