Precision Medicine

Going Beyond Genomics in Precision Medicine: What’s Next

Precision medicine processes, while involving genomics, are not confined to working with data about an individual’s genes, environment, and lifestyle. Precision medicine also means putting patients on the right path of care, taking into consideration other individual tolerances, such as participation and cost. Precision medicine processes incorporate data beyond the individual, pulling in socio-economic data, as well as relevant internal and external data, to create an entire patient data ecosystem. With reusable data modules, this information is processed within a closed-loop analytics framework to facilitate clinical decision making at the point of care. This optimizes clinical workflow, thus leading to more precise medicine.

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The Top 4 Ways De-Identified Data Improves Research

Level 1 of the Healthcare Analytics Adoption Model is providing de-identified data marts and self-service tools. Researchers navigating the complex research process can use de-identified data in each step of the process to increase their chances of having more successful research projects. Using de-identified data not only removes research roadblocks, but also enables researchers to navigate the four fundamental research steps with more ease. There are four specific ways de-identified data improves research:

  1. Enables early discovery and exploration to test the validity of the hypothesis before committing time and resources.
  2. Enables researchers to explore and refine their cohorts and determine whether the patient population can support the scope of the project.
  3. Enables researchers to put together strong grant applications without having to tax the resources of enterprise data analysts—and without having to wait for analysts to answer relatively straightforward questions.
  4. Enables researchers to come to the IRB with a strong, fully supported application. A data-driven research process ensures that both researchers and IRB reviewers don’t have to waste their time on projects that may not be viable.

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Turn Research Into Care Delivery Improvements Using the Research Analytics Adoption Model

Research is a complex yet vital component of improving care delivery, and it can be hindered by a variety of organizational and technical roadblocks:

  • Insufficient tools and processes
  • Poor infrastructure
  • No single source of truth for data
Health systems can overcome these common research roadblocks and turn analytics-powered research into care delivery improvements by using the Research Analytics Adoption model as a strategic roadmap. The model consists of 8 levels designed to align operations and research priorities:
  1. De-identified tools and data marts
  2. Delivery of customized data sets
  3. EDW-facilitated study recruitment
  4. Centralized, research-specific data collection
  5. Automated research operations reporting
  6. Biobank/genomic data integration
  7. Multi-site data sharing
  8. Translational Analytics

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The 3 Challenges of Translational and Clinical Research Data Management and a Strategy to Succeed

Researchers are facing problems with clinical research data management. These challenges include: 1. Accessing healthcare data due to technology barriers, regulatory barriers, and organizational barriers; 2. Inefficient use of time and resources when working with the data because of poor study recruitment, data cobbling with Excel and Access databases, and materials waste when samples can’t be found.; and 3. Translating research discovery into clinical practice because systems aren’t in place to move new best practices into everyday clinical care.

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